1 00:00:09,110 --> 00:00:07,110 a lot of important research to support 2 00:00:11,190 --> 00:00:09,120 future deep space exploration is 3 00:00:13,749 --> 00:00:11,200 underway on the international space 4 00:00:15,829 --> 00:00:13,759 station now with the one-year mission 5 00:00:19,269 --> 00:00:15,839 crew members scott kelly and mikhail 6 00:00:20,950 --> 00:00:19,279 konienko as scientists work to learn 7 00:00:22,230 --> 00:00:20,960 what it will take to support crews that 8 00:00:25,349 --> 00:00:22,240 one day will 9 00:00:29,189 --> 00:00:25,359 venture far beyond low earth orbit an 10 00:00:31,509 --> 00:00:29,199 investigation known as sleep iss 12 a 11 00:00:33,270 --> 00:00:31,519 follow-up to research on a previous 12 00:00:35,830 --> 00:00:33,280 station missions as well as space 13 00:00:37,830 --> 00:00:35,840 shuttle missions focuses on the quality 14 00:00:39,670 --> 00:00:37,840 and the quantity of sleep for the crew 15 00:00:41,750 --> 00:00:39,680 members and how that impacts their 16 00:00:43,510 --> 00:00:41,760 health and performance this morning 17 00:00:46,389 --> 00:00:43,520 we're going to learn more about that 18 00:00:48,790 --> 00:00:46,399 from the principal investigator dr laura 19 00:00:49,830 --> 00:00:48,800 barger of the harvard medical school and 20 00:00:52,549 --> 00:00:49,840 brigham 21 00:00:54,709 --> 00:00:52,559 and women's hospital in boston 22 00:00:55,510 --> 00:00:54,719 good morning laura thank you for joining 23 00:00:57,750 --> 00:00:55,520 us 24 00:00:59,750 --> 00:00:57,760 good morning thanks for having me 25 00:01:01,990 --> 00:00:59,760 well let's just start with uh this this 26 00:01:04,469 --> 00:01:02,000 sleep can you i mean obviously we all 27 00:01:06,469 --> 00:01:04,479 need sleep right here on earth but um 28 00:01:08,789 --> 00:01:06,479 explain to me why is this important to 29 00:01:10,469 --> 00:01:08,799 learn about the quality and the quantity 30 00:01:12,390 --> 00:01:10,479 of sleep that the astronauts are getting 31 00:01:14,870 --> 00:01:12,400 there in space 32 00:01:16,950 --> 00:01:14,880 well because sleep is so important it's 33 00:01:20,390 --> 00:01:16,960 it like you said it's important for 34 00:01:23,030 --> 00:01:20,400 everyone sleep deficiency here on earth 35 00:01:25,590 --> 00:01:23,040 leads to negative health and performance 36 00:01:28,469 --> 00:01:25,600 and safety consequences 37 00:01:31,069 --> 00:01:28,479 sleep is a biological need 38 00:01:33,270 --> 00:01:31,079 it can't be overcome by training or 39 00:01:36,789 --> 00:01:33,280 professionalism or having the right 40 00:01:41,270 --> 00:01:36,799 stuff in general adults need to sleep 41 00:01:43,030 --> 00:01:41,280 seven to nine hours per night and um 42 00:01:46,069 --> 00:01:43,040 as the us population everyone is 43 00:01:48,230 --> 00:01:46,079 sleeping less now than they used to 50 44 00:01:51,270 --> 00:01:48,240 years ago only three percent of the 45 00:01:55,270 --> 00:01:51,280 population was sleeping six hours a 46 00:01:57,510 --> 00:01:55,280 night or less and now 30 of us adults 47 00:01:59,590 --> 00:01:57,520 report sleeping 48 00:02:02,469 --> 00:01:59,600 less than six hours a night and that's 49 00:02:06,310 --> 00:02:02,479 44 when you look at night shift workers 50 00:02:08,150 --> 00:02:06,320 so sleep deficiency is a big problem um 51 00:02:10,949 --> 00:02:08,160 like i said it impairs your health and 52 00:02:13,990 --> 00:02:10,959 it prepares your performance and your 53 00:02:16,390 --> 00:02:14,000 mood uh your productivity so obviously 54 00:02:19,350 --> 00:02:16,400 for the astronauts up in space who have 55 00:02:24,150 --> 00:02:19,360 to perform well all the time have to be 56 00:02:26,070 --> 00:02:24,160 very productive sleep deficiency is um 57 00:02:28,070 --> 00:02:26,080 would would not be a good thing to have 58 00:02:32,070 --> 00:02:28,080 in space and they need to get a 59 00:02:33,750 --> 00:02:32,080 sufficient quantity and quality of sleep 60 00:02:35,270 --> 00:02:33,760 well thank you so much for that i i can 61 00:02:37,110 --> 00:02:35,280 certainly understand i don't think 62 00:02:39,110 --> 00:02:37,120 performance perform as well here on 63 00:02:40,470 --> 00:02:39,120 earth when i don't have enough sleep can 64 00:02:42,470 --> 00:02:40,480 you tell me i understand you've been 65 00:02:44,790 --> 00:02:42,480 doing this study since back on the 66 00:02:46,390 --> 00:02:44,800 shuttle mission so what have we learned 67 00:02:50,070 --> 00:02:46,400 so far 68 00:02:52,869 --> 00:02:50,080 well we we have been studying sleep for 69 00:02:55,990 --> 00:02:52,879 10 years we monitored the sleep of 70 00:02:57,430 --> 00:02:56,000 shuttle astronauts and astronauts on the 71 00:03:01,030 --> 00:02:57,440 iss 72 00:03:04,790 --> 00:03:01,040 so we had 80 crew members on shuttle 73 00:03:07,030 --> 00:03:04,800 missions and 21 iss crew members 74 00:03:10,229 --> 00:03:07,040 participate in our study 75 00:03:14,149 --> 00:03:10,239 and we found that the sleep on the 76 00:03:17,670 --> 00:03:14,159 shuttle was about six hours per night 77 00:03:19,910 --> 00:03:17,680 and what was most interesting i think as 78 00:03:21,190 --> 00:03:19,920 before we undertook the study we had 79 00:03:25,030 --> 00:03:21,200 thought that 80 00:03:27,430 --> 00:03:25,040 sleep was restricted on shuttle missions 81 00:03:30,309 --> 00:03:27,440 but on iss we had heard that people 82 00:03:32,550 --> 00:03:30,319 adapt and would sleep more and what we 83 00:03:36,070 --> 00:03:32,560 found was that on the 84 00:03:39,430 --> 00:03:36,080 uh station missions the astronauts um 85 00:03:41,110 --> 00:03:39,440 crew members only slept about 10 minutes 86 00:03:43,110 --> 00:03:41,120 more than they did on the shuttle 87 00:03:46,789 --> 00:03:43,120 missions 88 00:03:48,550 --> 00:03:46,799 so so that was a a surprise uh to us 89 00:03:50,550 --> 00:03:48,560 that we thought that they would be 90 00:03:52,470 --> 00:03:50,560 sleeping more on the longer duration 91 00:03:55,110 --> 00:03:52,480 missions and those missions 92 00:03:57,270 --> 00:03:55,120 averaged about six months 93 00:03:59,589 --> 00:03:57,280 do you have a hypothesis for 94 00:04:02,630 --> 00:03:59,599 what would happen for a person who is in 95 00:04:04,630 --> 00:04:02,640 space for an entire full year 96 00:04:06,630 --> 00:04:04,640 well that's going to be very interesting 97 00:04:09,750 --> 00:04:06,640 and um 98 00:04:12,309 --> 00:04:09,760 we don't know will people learn uh or be 99 00:04:14,309 --> 00:04:12,319 able to adapt are the schedules going to 100 00:04:17,349 --> 00:04:14,319 be different 101 00:04:19,590 --> 00:04:17,359 on the six month missions there were a 102 00:04:21,509 --> 00:04:19,600 lot of um 103 00:04:24,629 --> 00:04:21,519 during the time period where we studied 104 00:04:26,469 --> 00:04:24,639 the shuttle was coming up frequently 105 00:04:29,909 --> 00:04:26,479 there were other 106 00:04:31,110 --> 00:04:29,919 progress ships that came up and 107 00:04:33,590 --> 00:04:31,120 when a 108 00:04:36,710 --> 00:04:33,600 another vehicle uh docked with the 109 00:04:38,870 --> 00:04:36,720 station they had to shift their sleep 110 00:04:42,230 --> 00:04:38,880 wake schedule 111 00:04:44,469 --> 00:04:42,240 to accommodate the incoming vehicle and 112 00:04:47,510 --> 00:04:44,479 this puts a lot of 113 00:04:49,590 --> 00:04:47,520 challenge to the circadian system 114 00:04:51,430 --> 00:04:49,600 because they have to shift the timing of 115 00:04:54,150 --> 00:04:51,440 their sleep wake schedule it's like 116 00:04:55,510 --> 00:04:54,160 traveling across time zones and then 117 00:04:58,070 --> 00:04:55,520 they would 118 00:04:59,749 --> 00:04:58,080 shift their schedule back after the 119 00:05:01,430 --> 00:04:59,759 vehicle left 120 00:05:04,390 --> 00:05:01,440 and so 121 00:05:06,150 --> 00:05:04,400 we will see how much that occurs on this 122 00:05:07,749 --> 00:05:06,160 one year mission 123 00:05:09,670 --> 00:05:07,759 if that 124 00:05:11,110 --> 00:05:09,680 if those shifts occur throughout the 125 00:05:14,629 --> 00:05:11,120 one-year mission like they did the 126 00:05:17,430 --> 00:05:14,639 six-month mission we may see a lot of 127 00:05:20,550 --> 00:05:17,440 the same sleep deficiency taking place a 128 00:05:21,990 --> 00:05:20,560 lot of those circadian challenges 129 00:05:24,150 --> 00:05:22,000 and you're studying the one-year crew 130 00:05:26,790 --> 00:05:24,160 members that would be astronaut scott 131 00:05:28,629 --> 00:05:26,800 kelly and also mikhail konienko can you 132 00:05:30,870 --> 00:05:28,639 tell me what it is that they do to 133 00:05:31,909 --> 00:05:30,880 participate in this particular study for 134 00:05:34,150 --> 00:05:31,919 you 135 00:05:36,870 --> 00:05:34,160 sure we're using the same protocol that 136 00:05:39,270 --> 00:05:36,880 we use during the 10-year study so that 137 00:05:41,350 --> 00:05:39,280 we'll be able to compare 138 00:05:44,230 --> 00:05:41,360 the data that we collect in the one-year 139 00:05:46,469 --> 00:05:44,240 mission with the other data collection 140 00:05:49,110 --> 00:05:46,479 and what we have the the crew members do 141 00:05:51,830 --> 00:05:49,120 first of all prior to 142 00:05:53,830 --> 00:05:51,840 flight we collect data to see how they 143 00:05:54,950 --> 00:05:53,840 sleep here on earth 144 00:05:57,029 --> 00:05:54,960 and then 145 00:05:59,270 --> 00:05:57,039 during the mission we monitor sleep 146 00:06:01,510 --> 00:05:59,280 throughout the mission and then we study 147 00:06:03,590 --> 00:06:01,520 it post flight as well 148 00:06:07,270 --> 00:06:03,600 during the study intervals what we have 149 00:06:09,350 --> 00:06:07,280 the crew member do is wear an actograph 150 00:06:12,150 --> 00:06:09,360 or an act a watch 151 00:06:14,150 --> 00:06:12,160 it it looks um something like the 152 00:06:15,590 --> 00:06:14,160 wearables that you see other people 153 00:06:17,510 --> 00:06:15,600 wearing 154 00:06:19,749 --> 00:06:17,520 to monitor their sleep here on earth 155 00:06:22,710 --> 00:06:19,759 like the fitbits or the jawbones or 156 00:06:25,270 --> 00:06:22,720 those type of devices we use a research 157 00:06:27,830 --> 00:06:25,280 quality device it's an accelerometer 158 00:06:30,550 --> 00:06:27,840 that measures motion of the wrist 159 00:06:33,510 --> 00:06:30,560 so they wear this continuously 160 00:06:34,710 --> 00:06:33,520 throughout the data collection periods 161 00:06:35,830 --> 00:06:34,720 and 162 00:06:39,749 --> 00:06:35,840 that 163 00:06:42,710 --> 00:06:39,759 we're able to use a software algorithm 164 00:06:44,309 --> 00:06:42,720 that estimates how much sleep the crew 165 00:06:48,469 --> 00:06:44,319 member is getting 166 00:06:50,230 --> 00:06:48,479 also we have the crew member fill out a 167 00:06:52,950 --> 00:06:50,240 daily log 168 00:06:54,950 --> 00:06:52,960 and on that log they tell us how much 169 00:06:56,950 --> 00:06:54,960 they think they slept 170 00:06:59,270 --> 00:06:56,960 and when they went to bed and when they 171 00:07:01,670 --> 00:06:59,280 got up that helps us interpret the 172 00:07:04,070 --> 00:07:01,680 actigraphy data we're collecting 173 00:07:06,710 --> 00:07:04,080 also on that log we're able to collect 174 00:07:09,189 --> 00:07:06,720 information about 175 00:07:11,189 --> 00:07:09,199 their subjective sleep quality and how 176 00:07:13,670 --> 00:07:11,199 alert they feel 177 00:07:16,870 --> 00:07:13,680 and we ask them about counter measures 178 00:07:19,350 --> 00:07:16,880 that they use so are they using caffeine 179 00:07:21,990 --> 00:07:19,360 to help them maintain alertness are they 180 00:07:23,990 --> 00:07:22,000 taking medications to help them 181 00:07:25,430 --> 00:07:24,000 go to sleep at night 182 00:07:27,990 --> 00:07:25,440 and 183 00:07:28,870 --> 00:07:28,000 on earth they fill out that log every 184 00:07:31,110 --> 00:07:28,880 day 185 00:07:33,430 --> 00:07:31,120 that during the data collection period 186 00:07:35,430 --> 00:07:33,440 and up in space they fill that out about 187 00:07:37,270 --> 00:07:35,440 every third week 188 00:07:39,110 --> 00:07:37,280 and are they wearing the actor watch 189 00:07:40,629 --> 00:07:39,120 every day i know we've actually seen 190 00:07:42,710 --> 00:07:40,639 i've seen several people ask the 191 00:07:44,629 --> 00:07:42,720 question why they were two watches and i 192 00:07:46,150 --> 00:07:44,639 guess one of them is for them to tell 193 00:07:48,629 --> 00:07:46,160 time and then the other one is the actor 194 00:07:49,830 --> 00:07:48,639 watch for this particular sleep study so 195 00:07:51,350 --> 00:07:49,840 is this something that they're wearing 196 00:07:52,950 --> 00:07:51,360 continuously throughout the entire 197 00:07:54,550 --> 00:07:52,960 mission 198 00:07:57,110 --> 00:07:54,560 right so they wear it throughout the 199 00:07:59,270 --> 00:07:57,120 entire one-year mission and so we're 200 00:08:01,670 --> 00:07:59,280 going to have a lot of great data that 201 00:08:03,749 --> 00:08:01,680 we'll be able to analyze to look at 202 00:08:06,629 --> 00:08:03,759 their sleep on a day-to-day basis 203 00:08:08,550 --> 00:08:06,639 throughout the whole year in space 204 00:08:10,230 --> 00:08:08,560 how long will they be wearing this when 205 00:08:12,390 --> 00:08:10,240 they come home so that you can do some 206 00:08:14,950 --> 00:08:12,400 kind of comparative studies right so 207 00:08:16,950 --> 00:08:14,960 just for a couple weeks uh after they 208 00:08:20,790 --> 00:08:16,960 land and we will look at what we would 209 00:08:22,790 --> 00:08:20,800 call recovery sleep if they have a lost 210 00:08:26,390 --> 00:08:22,800 sleep in space or have any sleep 211 00:08:27,110 --> 00:08:26,400 deficiency then we see um 212 00:08:44,630 --> 00:08:27,120 a 213 00:08:46,230 --> 00:08:44,640 sleep 214 00:08:47,670 --> 00:08:46,240 thank you so much laura we really 215 00:08:49,350 --> 00:08:47,680 appreciate you coming out and talk 216 00:08:50,949 --> 00:08:49,360 talking with us good luck on the rest of 217 00:08:52,310 --> 00:08:50,959 your research and we look forward to 218 00:08:55,190 --> 00:08:52,320 hearing about the results of the one 219 00:08:56,790 --> 00:08:55,200 year crew mission and best of luck to